Nature

Regulation of MHC class II gene expression by the class II transactivator

MHC class II molecules are of central importance to the adaptive immune system. MHC-class-II-mediated peptide presentation is essential for positive and negative selection of CD4 + T cells in the ...
Nature

Regulation of major histocompatibility complex class II gene expression, genetic variation and disease

Major histocompatibility complex (MHC) class II molecules are cell-surface glycoproteins that play a central role in the immune system by presenting peptides to the antigen receptor of CD4+ T cells. 1 ...